Gene
si:ch1073-280e3.1
- ID
- ZDB-GENE-110411-261
- Name
- si:ch1073-280e3.1
- Symbol
- si:ch1073-280e3.1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have serine-type endopeptidase activity. Predicted to be involved in complement activation and proteolysis. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in Alzheimer's disease; age related macular degeneration 14; complement component 2 deficiency; macular degeneration; and psoriasis. Orthologous to human C2 (complement C2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR018114 | Serine proteases, trypsin family, histidine active site |
| Domain | IPR000436 | Sushi/SCR/CCP domain |
| Domain | IPR001254 | Serine proteases, trypsin domain |
| Domain | IPR002035 | von Willebrand factor, type A |
| Family | IPR001314 | Peptidase S1A, chymotrypsin family |
| Family | IPR011360 | Complement B/C2 |
| Homologous_superfamily | IPR009003 | Peptidase S1, PA clan |
| Homologous_superfamily | IPR035976 | Sushi/SCR/CCP superfamily |
| Homologous_superfamily | IPR036465 | von Willebrand factor A-like domain superfamily |
| Homologous_superfamily | IPR043504 | Peptidase S1, PA clan, chymotrypsin-like fold |
Domain Details Per Protein
| Protein | Length | Complement B/C2 | Peptidase S1A, chymotrypsin family | Peptidase S1, PA clan | Peptidase S1, PA clan, chymotrypsin-like fold | Serine proteases, trypsin domain | Serine proteases, trypsin family, histidine active site | Sushi/SCR/CCP domain | Sushi/SCR/CCP superfamily | von Willebrand factor A-like domain superfamily | von Willebrand factor, type A |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1QJB3
|
831 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:ch1073-280e3.1-201
(1)
|
Ensembl | 2,647 nt |
Interactions and Pathways
No data available
Plasmids
No data available