Gene
unc13d
- ID
- ZDB-GENE-110411-188
- Name
- unc-13 homolog D (C. elegans)
- Symbol
- unc13d Nomenclature History
- Previous Names
-
- si:ch211-140l3.2
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to be involved in secretion. Predicted to act upstream of or within exocytosis. Predicted to be located in late endosome and recycling endosome. Predicted to be active in exocytic vesicle. Human ortholog(s) of this gene implicated in familial hemophagocytic lymphohistiocytosis 3. Orthologous to human UNC13D (unc-13 homolog D).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial hemophagocytic lymphohistiocytosis 3 | Alliance | Hemophagocytic lymphohistiocytosis, familial, 3 | 608898 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | C2 domain | C2 domain superfamily | Mammalian uncoordinated homology 13, domain 2 | Munc13 homology 1 | MUN domain | UNC-13 domain-containing protein |
|---|---|---|---|---|---|---|---|
|
UniProtKB:F6NFN1
|
1105 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
unc13d-201
(1)
|
Ensembl | 4,008 nt | ||
| mRNA |
unc13d-202
(1)
|
Ensembl | 773 nt | ||
| mRNA |
unc13d-203
(1)
|
Ensembl | 3,237 nt |
Interactions and Pathways
No data available
Plasmids
No data available