Gene

cass4

ID
ZDB-GENE-110131-9
Name
Cas scaffold protein family member 4
Symbol
cass4 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to be involved in cell migration and cell surface receptor protein tyrosine kinase signaling pathway. Predicted to act upstream of or within cell adhesion. Predicted to be located in focal adhesion. Predicted to be active in cytoplasm. Predicted to colocalize with plasma membrane. Orthologous to human CASS4 (Cas scaffold protein family member 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa14486Allele with one point mutationUnknownPremature StopENU
sa17485Allele with one point mutationUnknownPremature StopENU
sa31836Allele with one point mutationUnknownPremature StopENU
sa35101Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With cass4 Human Ortholog
No data available
Associated With cass4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001452 SH3 domain
Domain IPR014928 Serine rich protein interaction domain
Domain IPR021901 CAS family, C-terminal
Domain IPR035744 Cas scaffolding protein family member 4, SH3 domain
Family IPR037362 CAS family
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Domain Details Per Protein
Protein Additional Resources Length CAS family CAS family, C-terminal Cas scaffolding protein family member 4, SH3 domain CAS, serine rich four helix bundle domain superfamily Serine rich protein interaction domain SH3 domain SH3-like domain superfamily
UniProtKB:E7FDH3 InterPro 793
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 11
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA cass4-201 (1) Ensembl 3,027 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-14F19ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Species Symbol Chromosome Accession # Evidence
HumanCASS420
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseCass42
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations