Gene
zbtb16b
- ID
- ZDB-GENE-100923-1
- Name
- zinc finger and BTB domain containing 16b
- Symbol
- zbtb16b Nomenclature History
- Previous Names
-
- plzfb (1)
- wu:fb53a11
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of type I interferon production. Localizes to nucleus. Is expressed in several structures, including anterior neural keel; hindbrain neural keel; integument; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in acute promyelocytic leukemia. Orthologous to human ZBTB16 (zinc finger and BTB domain containing 16).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Leukemia, acute promyelocytic, PL2F/RARA type |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | BTB/POZ domain | SKP1/BTB/POZ domain superfamily | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|---|
|
UniProtKB:E7FGS1
|
659 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
zbtb16b-201
(1)
|
Ensembl | 8,939 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance