Gene
ulk4
- ID
- ZDB-GENE-100922-243
- Name
- unc-51 like kinase 4
- Symbol
- ulk4 Nomenclature History
- Previous Names
-
- si:ch211-101b18.1
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable ATP binding activity and protein kinase activity. Predicted to act upstream of or within protein phosphorylation. Orthologous to human ULK4 (unc-51 like kinase 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa792 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa6405 | Allele with one point mutation | Unknown | Missense, Splice Site | ENU | |
| sa16618 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa17493 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa22745 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa36032 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa36033 | Allele with one point mutation | Unknown | Missense, Splice Site | ENU | |
| sa36034 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000719 | Protein kinase domain |
| Family | IPR045906 | Serine/threonine-protein kinase ULK4 |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR011989 | Armadillo-like helical |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
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Domain Details Per Protein
| Protein | Length | Armadillo-like helical | Armadillo-type fold | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase ULK4 |
|---|---|---|---|---|---|---|
|
UniProtKB:E7F1L0
|
1285 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-12E20 | ZFIN Curated Data | |
| Contained in | BAC | CH73-49B13 | ZFIN Curated Data | |
| Contained in | BAC | CH211-85D13 | ZFIN Curated Data | |
| Contained in | BAC | CH211-101B18 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_068214079 (1) | 4310 nt | ||
| Genomic | GenBank:BX511115 (2) | 169614 nt | ||
| Polypeptide | UniProtKB:E7F1L0 (1) | 1285 aa |
- Comparative Orthology
- Alliance
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Briolat, V., Jouneau, L., Carvalho, R., Palha, N., Langevin, C., Herbomel, P., Schwartz, O., Spaink, H.P., Levraud, J.P., Boudinot, P. (2014) Contrasted Innate Responses to Two Viruses in Zebrafish: Insights into the Ancestral Repertoire of Vertebrate IFN-Stimulated Genes. Journal of immunology (Baltimore, Md. : 1950). 192:4328-41
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