Gene
fkbp10a
- ID
- ZDB-GENE-100921-75
- Name
- FKBP prolyl isomerase 10a
- Symbol
- fkbp10a Nomenclature History
- Previous Names
-
- si:ch73-218h2.1
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to have calcium ion binding activity and peptidyl-prolyl cis-trans isomerase activity. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 11. Orthologous to human FKBP10 (FKBP prolyl isomerase 10).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Bruck syndrome | Alliance | Bruck syndrome 1 | 259450 |
| osteogenesis imperfecta type 11 | Alliance | Osteogenesis imperfecta, type XI | 610968 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR018247 | EF-Hand 1, calcium-binding site |
| Domain | IPR001179 | FKBP-type peptidyl-prolyl cis-trans isomerase domain |
| Domain | IPR002048 | EF-hand domain |
| Family | IPR051989 | FK506-binding protein-like isomerase |
| Homologous_superfamily | IPR011992 | EF-hand domain pair |
| Homologous_superfamily | IPR046357 | Peptidyl-prolyl cis-trans isomerase domain superfamily |
Domain Details Per Protein
| Protein | Length | EF-Hand 1, calcium-binding site | EF-hand domain | EF-hand domain pair | FK506-binding protein-like isomerase | FKBP-type peptidyl-prolyl cis-trans isomerase domain | Peptidyl-prolyl cis-trans isomerase domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2B6F8
|
510 | ||||||
|
UniProtKB:A0A8M2B6A9
|
352 | ||||||
|
UniProtKB:A0A8M9PBG3
|
563 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
fkbp10a-201
(1)
|
Ensembl | 1,978 nt |
Interactions and Pathways
No data available
Plasmids
No data available