Gene
brwd3
- ID
- ZDB-GENE-100921-43
- Name
- bromodomain and WD repeat domain containing 3
- Symbol
- brwd3 Nomenclature History
- Previous Names
-
- si:dkey-237j10.3
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to be involved in cytoskeleton organization; regulation of cell shape; and regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Orthologous to human BRWD3 (bromodomain and WD repeat domain containing 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| non-syndromic X-linked intellectual disability 93 | Alliance | Intellectual developmental disorder, X-linked 93 | 300659 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018359 | Bromodomain, conserved site |
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Domain | IPR001487 | Bromodomain |
| Family | IPR052060 | Bromodomain and WD repeat-containing |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Homologous_superfamily | IPR036427 | Bromodomain-like superfamily |
| Repeat | IPR001680 | WD40 repeat |
Domain Details Per Protein
| Protein | Length | Bromodomain | Bromodomain and WD repeat-containing | Bromodomain, conserved site | Bromodomain-like superfamily | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B2F0
|
1741 | ||||||||
|
UniProtKB:A0A8M9Q1J4
|
1740 | ||||||||
|
UniProtKB:A0A8M3ASD3
|
1742 | ||||||||
|
UniProtKB:A0A8M9PQW9
|
1741 |
Interactions and Pathways
No data available
Plasmids
No data available