Gene

stx1a

ID
ZDB-GENE-100802-1
Name
syntaxin 1A (brain)
Symbol
stx1a Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to have SNAP receptor activity and SNARE binding activity. Predicted to be involved in intracellular protein transport; synaptic vesicle fusion to presynaptic active zone membrane; and vesicle docking. Predicted to localize to several cellular components, including SNARE complex; presynaptic active zone membrane; and synaptic vesicle. Human ortholog(s) of this gene implicated in Creutzfeldt-Jakob disease and Hirschsprung's disease. Orthologous to human STX1A (syntaxin 1A).
Genome Resources
Note
Represented by LOC100006625 and ENSDARG00000058994 on LG15 in Zv8.
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With stx1a Human Ortholog
No data available
Associated With stx1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR006012 Syntaxin/epimorphin, conserved site
Domain IPR000727 Target SNARE coiled-coil homology domain
Domain IPR006011 Syntaxin, N-terminal domain
Family IPR045242 Syntaxin
Homologous_superfamily IPR010989 SNARE
Domain Details Per Protein
Protein Length SNARE Syntaxin Syntaxin/epimorphin, conserved site Syntaxin, N-terminal domain Target SNARE coiled-coil homology domain
UniProtKB:A0A8M1PT03 291
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA stx1a-201 (1) Ensembl 867 nt
mRNA stx1a-202 (1) Ensembl 840 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations