Gene
arhgef25a
- ID
- ZDB-GENE-100728-4
- Name
- Rho guanine nucleotide exchange factor (GEF) 25a
- Symbol
- arhgef25a Nomenclature History
- Previous Names
-
- fk20e09
- gb:go935858
- unm_sa37737
- unm_sa39412
- wu:fk20e09
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in axon guidance. Predicted to be active in cytoplasm. Predicted to be extrinsic component of membrane. Orthologous to human ARHGEF25 (Rho guanine nucleotide exchange factor 25).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR055251 | SOS1/NGEF-like, PH domain |
| Family | IPR051336 | Rho GTPase-activating Guanine Nucleotide Exchange Factors |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR035899 | Dbl homology (DH) domain superfamily |
Domain Details Per Protein
| Protein | Length | Dbl homology (DH) domain superfamily | PH-like domain superfamily | Pleckstrin homology domain | Rho GTPase-activating Guanine Nucleotide Exchange Factors | SOS1/NGEF-like, PH domain |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3AYL2
|
732 | |||||
|
UniProtKB:A0A8M3AVJ0
|
685 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
arhgef25-201
(1)
|
Ensembl | 1,617 nt |
Interactions and Pathways
No data available
Plasmids
No data available