Gene
aldh1l1
- ID
- ZDB-GENE-100519-4
- Name
- aldehyde dehydrogenase 1 family, member L1
- Symbol
- aldh1l1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Exhibits formyltetrahydrofolate dehydrogenase activity and hydrolase activity. Involved in animal organ development and gastrulation. Predicted to localize to cytosol. Is expressed in several structures, including cardiovascular system; digestive system; fin; hematopoietic system; and nervous system. Orthologous to human ALDH1L1 (aldehyde dehydrogenase 1 family member L1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Chang et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR001555 | Phosphoribosylglycinamide formyltransferase, active site |
| Conserved_site | IPR016160 | Aldehyde dehydrogenase, cysteine active site |
| Conserved_site | IPR029510 | Aldehyde dehydrogenase, glutamic acid active site |
| Domain | IPR002376 | Formyl transferase, N-terminal |
| Domain | IPR005793 | Formyl transferase, C-terminal |
| Domain | IPR009081 | Phosphopantetheine binding ACP domain |
| Domain | IPR015590 | Aldehyde dehydrogenase domain |
| Family | IPR011407 | 10-formyltetrahydrofolate dehydrogenase |
| Homologous_superfamily | IPR011034 | Formyl transferase-like, C-terminal domain superfamily |
| Homologous_superfamily | IPR016161 | Aldehyde/histidinol dehydrogenase |
| Homologous_superfamily | IPR016162 | Aldehyde dehydrogenase, N-terminal |
| Homologous_superfamily | IPR016163 | Aldehyde dehydrogenase, C-terminal |
| Homologous_superfamily | IPR036477 | Formyl transferase, N-terminal domain superfamily |
| Homologous_superfamily | IPR036736 | ACP-like superfamily |
| Homologous_superfamily | IPR037022 | Formyl transferase, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | 10-formyltetrahydrofolate dehydrogenase | ACP-like superfamily | Aldehyde dehydrogenase, C-terminal | Aldehyde dehydrogenase, cysteine active site | Aldehyde dehydrogenase domain | Aldehyde dehydrogenase, glutamic acid active site | Aldehyde dehydrogenase, N-terminal | Aldehyde/histidinol dehydrogenase | Formyl transferase, C-terminal | Formyl transferase, C-terminal domain superfamily | Formyl transferase-like, C-terminal domain superfamily | Formyl transferase, N-terminal | Formyl transferase, N-terminal domain superfamily | Phosphopantetheine binding ACP domain | Phosphoribosylglycinamide formyltransferase, active site |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E3NZ06
|
903 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
aldh1l1-201
(1)
|
Ensembl | 5,863 nt |
Interactions and Pathways
No data available
Plasmids
No data available