Gene
washc4
- ID
- ZDB-GENE-100427-4
- Name
- WASH complex subunit 4
- Symbol
- washc4 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Involved in regulation of autophagy. Predicted to localize to WASH complex and endosome. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human WASHC4 (WASH complex subunit 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Kustermann et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Kustermann et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 43 | Alliance | Intellectual developmental disorder, autosomal recessive 43 | 615817 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | WASH complex subunit 4, N-terminal | WASH complex subunit 7 | WASH complex subunit 7, central domain | WASH complex subunit 7, C-terminal |
|---|---|---|---|---|---|
|
UniProtKB:E7F4L4
|
1173 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
washc4-201
(1)
|
Ensembl | 5,366 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance