Gene
git1
- ID
- ZDB-GENE-100408-5
- Name
- G protein-coupled receptor kinase interacting ArfGAP 1
- Symbol
- git1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have GTPase activator activity and metal ion binding activity. Involved in angiogenesis. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder. Is expressed in head. Orthologous to human GIT1 (GIT ArfGAP 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Liu et al., 2012
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Liu et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR001164 | Arf GTPase activating protein |
Domain | IPR013724 | GIT, Spa2 homology (SHD) domain |
Domain | IPR022018 | ARF GTPase-activating protein GIT1, C-terminal |
Domain | IPR032352 | Arf GTPase-activating protein GIT1/2, coiled-coil domain |
Family | IPR047161 | ARF GTPase-activating protein Git-like |
Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
Homologous_superfamily | IPR037278 | ARFGAP/RecO-like zinc finger |
Homologous_superfamily | IPR038508 | ArfGAP domain superfamily |
Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
Protein | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | ArfGAP domain superfamily | ARFGAP/RecO-like zinc finger | Arf GTPase activating protein | Arf GTPase-activating protein GIT1/2, coiled-coil domain | ARF GTPase-activating protein GIT1, C-terminal | ARF GTPase-activating protein Git-like | GIT, Spa2 homology (SHD) domain |
---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M3AHJ1
|
667 | |||||||||
UniProtKB:A0A0R4IPR8
|
761 | |||||||||
UniProtKB:E7FAZ2
|
752 |
Interactions and Pathways
No data available
Plasmids
No data available