Gene

afap1l2

ID
ZDB-GENE-100318-1
Name
actin filament associated protein 1-like 2
Symbol
afap1l2 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have SH2 domain binding activity and SH3 domain binding activity. Involved in closure of optic fissure. Predicted to localize to cytosol. Is expressed in diencephalon; forebrain; optic cup; optic furrow; and optic stalk. Orthologous to human AFAP1L2 (actin filament associated protein 1 like 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Cao et al., 2018
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Cao et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With afap1l2 Human Ortholog
No data available
Associated With afap1l2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001849 Pleckstrin homology domain
Family IPR030113 Actin-filament associated protein
Homologous_superfamily IPR011993 PH-like domain superfamily
Domain Details Per Protein
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA afap1l2-201 (1) Ensembl 3,347 nt
mRNA afap1l2-202 (1) Ensembl 2,988 nt
mRNA afap1l2-203 (1) Ensembl 2,879 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations