Gene
nlgn4xb
- ID
- ZDB-GENE-100309-1
- Name
- neuroligin 4 X-linked b
- Symbol
- nlgn4xb Nomenclature History
- Previous Names
-
- nlgn4a (1)
- nlgn4b
- Type
- protein_coding_gene
- Location
- Ambiguous Mapping Details/Browsers
- Description
- Predicted to enable neurexin family protein binding activity and signaling receptor activity. Predicted to be involved in several processes, including neuron cell-cell adhesion; synapse assembly; and synaptic vesicle endocytosis. Predicted to act upstream of or within cell adhesion. Predicted to be located in cell junction and plasma membrane. Predicted to be active in cell surface and postsynaptic specialization membrane. Is expressed in several structures, including brain; cranial ganglion; eye; gonad; and swim bladder. Human ortholog(s) of this gene implicated in Asperger syndrome and autistic disorder. Orthologous to human NLGN4X (neuroligin 4 X-linked).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Alpha/Beta hydrolase fold | Carboxylesterase, type B | Carboxylesterase type B, conserved site | Neuroligin | Neuroligin and Bile salt-activated lipase |
|---|---|---|---|---|---|---|
|
UniProtKB:F1QK81
|
795 | |||||
|
UniProtKB:D0EVX3
|
795 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nlgn4xb-201
(1)
|
Ensembl | 2,900 nt | ||
| mRNA |
nlgn4xb-202
(1)
|
Ensembl | 2,679 nt | ||
| mRNA |
nlgn4xb-203
(1)
|
Ensembl | 2,880 nt |
Interactions and Pathways
No data available
Plasmids
No data available