Gene
brcc3
- ID
- ZDB-GENE-100215-1
- Name
- BRCA1/BRCA2-containing complex, subunit 3
- Symbol
- brcc3 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have metallopeptidase activity; polyubiquitin modification-dependent protein binding activity; and thiol-dependent ubiquitin-specific protease activity. Involved in angiogenesis. Predicted to localize to BRCA1-A complex and BRISC complex. Is expressed in axial vasculature and head. Orthologous to human BRCC3 (BRCA1/BRCA2-containing complex subunit 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Miskinyte et al., 2011
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Miskinyte et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | BRCC36, C-terminal helical domain | Brcc36 isopeptidase | JAB1/MPN/MOV34 metalloenzyme domain | JAMM/MPN+ metalloenzymes, peptidase M67A | MPN domain |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B525
|
287 |
Interactions and Pathways
No data available
Plasmids
No data available