Gene
kcnn2
- ID
- ZDB-GENE-091116-41
- Name
- potassium calcium-activated channel subfamily N member 2
- Symbol
- kcnn2 Nomenclature History
- Previous Names
-
- si:dkey-76p7.5
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable calmodulin binding activity and small conductance calcium-activated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to act upstream of or within monoatomic ion transmembrane transport and potassium ion transport. Predicted to be located in membrane. Predicted to be active in neuron projection; neuronal cell body; and plasma membrane. Is expressed in several structures, including brain; heart; neural rod; neural tube; and tail bud. Human ortholog(s) of this gene implicated in myoclonic dystonia 34. Orthologous to human KCNN2 (potassium calcium-activated channel subfamily N member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| myoclonic dystonia 34 | Alliance | ?Dystonia 34, myoclonic | 619724 |
| Neurodevelopmental disorder with or without variable movement or behavioral abnormalities | 619725 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Calmodulin-binding domain | Potassium channel, calcium-activated, SK | Potassium channel domain | SK, calmodulin-binding domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M2B2K1
|
571 | ||||
|
UniProtKB:A0A8N7UVC3
|
677 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
kcnn2-201
(1)
|
Ensembl | 1,684 nt | ||
| ncRNA |
si:dkey-76p7.5-002
(1)
|
Ensembl | 287 nt |
Interactions and Pathways
No data available
Plasmids