Gene
erap1a
- ID
- ZDB-GENE-091113-7
- Name
- endoplasmic reticulum aminopeptidase 1a
- Symbol
- erap1a Nomenclature History
- Previous Names
-
- si:dkey-24n17.6
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Predicted to be involved in peptide catabolic process and proteolysis. Predicted to be active in cytoplasm; extracellular space; and membrane. Human ortholog(s) of this gene implicated in cervix carcinoma. Orthologous to human ERAP1 (endoplasmic reticulum aminopeptidase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR014782 | Peptidase M1, membrane alanine aminopeptidase |
| Domain | IPR024571 | ERAP1-like C-terminal domain |
| Domain | IPR045357 | Aminopeptidase N-like , N-terminal domain |
| Family | IPR001930 | Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase |
| Family | IPR034016 | Aminopeptidase N-type |
| Family | IPR050344 | Peptidase M1 family aminopeptidases |
| Homologous_superfamily | IPR027268 | Peptidase M4/M1, CTD superfamily |
| Homologous_superfamily | IPR042097 | Aminopeptidase N-like , N-terminal domain superfamliy |
Domain Details Per Protein
| Protein | Additional Resources | Length | Aminopeptidase N-like , N-terminal domain | Aminopeptidase N-like , N-terminal domain superfamliy | Aminopeptidase N-type | ERAP1-like C-terminal domain | Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase | Peptidase M1 family aminopeptidases | Peptidase M1, membrane alanine aminopeptidase | Peptidase M4/M1, CTD superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9Q695 | InterPro | 918 | ||||||||
| UniProtKB:A0A8M3B5Z1 | InterPro | 855 | ||||||||
| UniProtKB:A0A8M2B1Z9 | InterPro | 932 | ||||||||
| UniProtKB:A0A8M3AWF2 | InterPro | 933 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
erap1a-201
(1)
|
Ensembl | 3,323 nt |
Interactions and Pathways
No data available
Plasmids
No data available