Gene
ank1b
- ID
- ZDB-GENE-091113-6
- Name
- ankyrin 1, erythrocytic b
- Symbol
- ank1b Nomenclature History
- Previous Names
-
- si:ch211-263m18.3 (1)
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have ion channel binding activity. Predicted to be involved in protein localization to plasma membrane. Predicted to localize to axon initial segment and membrane. Human ortholog(s) of this gene implicated in anemia; hereditary spherocytosis; and hereditary spherocytosis type 1. Orthologous to human ANK1 (ankyrin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
hereditary spherocytosis type 1 | Alliance | Spherocytosis, type 1 | 182900 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000488 | Death domain |
Domain | IPR000906 | ZU5 domain |
Domain | IPR040745 | Ankyrin, UPA domain |
Family | IPR051165 | Multifunctional Ankyrin Repeat Domain-Containing Protein |
Homologous_superfamily | IPR011029 | Death-like domain superfamily |
Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
Protein | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | Ankyrin, UPA domain | Death domain | Death-like domain superfamily | Multifunctional Ankyrin Repeat Domain-Containing Protein | ZU5 domain |
---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M9PIW2
|
1930 | |||||||
UniProtKB:A0A8M9PD85
|
1956 | |||||||
UniProtKB:A0A8M9PR23
|
1963 | |||||||
UniProtKB:A0A8M9PUL5
|
1919 | |||||||
UniProtKB:A0A8M9PR28
|
1769 | |||||||
UniProtKB:A0A8M9PDB9
|
2091 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
ank1b-201
(1)
|
Ensembl | 5211 nt | |
mRNA |
ank1b-204
(1)
|
Havana | 5534 nt | |
mRNA |
ank1b-205
(1)
|
Ensembl | 5304 nt | |
mRNA |
ank1b-206
(1)
|
Ensembl | 4527 nt | |
mRNA |
ank1b-207
(1)
|
Ensembl | 3999 nt | |
mRNA |
ank1b-208
(1)
|
Ensembl | 5157 nt | |
ncRNA |
ank1b-003
(1)
|
Havana | 746 nt | |
ncRNA |
ank1b-004
(1)
|
Havana | 695 nt |
Interactions and Pathways
No data available
Plasmids
No data available