Gene
prex2
- ID
- ZDB-GENE-091113-37
- Name
- phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
- Symbol
- prex2 Nomenclature History
- Previous Names
-
- si:ch211-278g15.1
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to have Rac guanyl-nucleotide exchange factor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to localize to plasma membrane. Orthologous to human PREX2 (phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR001331 | Guanine-nucleotide dissociation stimulator, CDC24, conserved site |
Domain | IPR000219 | Dbl homology (DH) domain |
Domain | IPR000591 | DEP domain |
Domain | IPR001478 | PDZ domain |
Domain | IPR001849 | Pleckstrin homology domain |
Family | IPR051832 | Regulators of mTOR signaling and Rac activation |
Homologous_superfamily | IPR011993 | PH-like domain superfamily |
Homologous_superfamily | IPR035899 | Dbl homology (DH) domain superfamily |
Homologous_superfamily | IPR036034 | PDZ superfamily |
Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Domain Details Per Protein
Protein | Length | Dbl homology (DH) domain | Dbl homology (DH) domain superfamily | DEP domain | Guanine-nucleotide dissociation stimulator, CDC24, conserved site | PDZ domain | PDZ superfamily | PH-like domain superfamily | Pleckstrin homology domain | Regulators of mTOR signaling and Rac activation | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:E7F2H9
|
1600 |
Interactions and Pathways
No data available
Plasmids
No data available