Gene

slc4a5b

ID

ZDB-GENE-091112-19

Name

solute carrier family 4 member 5b

Symbol

slc4a5b Nomenclature History

Previous Names

slc4a5
sb:eu385
si:ch211-161n19.2

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to enable sodium:bicarbonate symporter activity. Predicted to be involved in bicarbonate transport; regulation of intracellular pH; and transmembrane transport. Predicted to act upstream of or within monoatomic anion transport. Predicted to be located in basolateral plasma membrane. Predicted to be active in plasma membrane. Is expressed in pronephric duct; retina; retinal photoreceptor layer; swim bladder; and swim bladder bud. Orthologous to human SLC4A5 (solute carrier family 4 member 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from Thisse et al., 2005

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

eu385 (11 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With slc4a5b Human Ortholog

No data available

Associated With slc4a5b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR011531	Bicarbonate transporter-like, transmembrane domain
Domain	IPR013769	Band 3 cytoplasmic domain
Family	IPR003020	Bicarbonate transporter, eukaryotic
Family	IPR003024	Sodium bicarbonate cotransporter
Homologous_superfamily	IPR016152	Phosphotransferase/anion transporter

Domain Details Per Protein

Protein	Length	Band 3 cytoplasmic domain	Bicarbonate transporter, eukaryotic	Bicarbonate transporter-like, transmembrane domain	Phosphotransferase/anion transporter	Sodium bicarbonate cotransporter
UniProtKB:A0A8M9QLB8 InterPro	1088
UniProtKB:A0A8M9PUG6 InterPro	1057
UniProtKB:A0A8M9QCR8 InterPro	1052
UniProtKB:A0A8M9Q6S5 InterPro	1054
UniProtKB:A0A8M9QLC1 InterPro	1050
UniProtKB:A0A8M9QHC7 InterPro	1038
UniProtKB:A0A8M9QHC3 InterPro	1088

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	slc4a5b-201 (1) Ensembl	Ensembl	6,115 nt	Select Tool ZFIN BLAST
mRNA	slc4a5b-202 (1) Ensembl	Ensembl	3,427 nt	Select Tool ZFIN BLAST
mRNA	slc4a5b-203 (1) Ensembl	Ensembl	3,123 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations