Gene

chn2

ID

ZDB-GENE-091020-5

Name

chimerin 2

Symbol

chn2 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to enable GTPase activator activity. Predicted to be involved in acrosome assembly. Predicted to act upstream of or within positive regulation of GTPase activity and signal transduction. Orthologous to human CHN2 (chimerin 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With chn2 Human Ortholog

No data available

Associated With chn2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000198	Rho GTPase-activating protein domain
Domain	IPR000980	SH2 domain
Domain	IPR002219	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Domain	IPR020454	Diacylglycerol/phorbol-ester binding
Domain	IPR035840	Chimaerin, SH2 domain
Domain	IPR037860	Chimaerin, RhoGAP domain
Family	IPR017356	Chimaerin
Family	IPR051854	Rho-type GTPase-activating protein
Homologous_superfamily	IPR008936	Rho GTPase activation protein
Homologous_superfamily	IPR036860	SH2 domain superfamily
Homologous_superfamily	IPR046349	C1-like domain superfamily

Domain Details Per Protein

Protein	Length	C1-like domain superfamily	Chimaerin	Chimaerin, RhoGAP domain	Chimaerin, SH2 domain	Diacylglycerol/phorbol-ester binding	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain	Rho GTPase-activating protein domain	Rho GTPase activation protein	Rho-type GTPase-activating protein	SH2 domain	SH2 domain superfamily
UniProtKB:E7F3K5 InterPro	466

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	chn2-201 (1) Ensembl	Ensembl	1,905 nt	Select Tool ZFIN BLAST
mRNA	chn2-202 (1) Ensembl	Ensembl	1,352 nt	Select Tool ZFIN BLAST
ncRNA	chn2-002 (1) Ensembl	Ensembl	611 nt	Select Tool ZFIN BLAST
ncRNA	chn2-003 (1) Ensembl	Ensembl	701 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations