ZFIN ID: ZDB-GENE-090918-1
Gene Name: neuroligin 1
Gene Symbol: nlgn1
Location: Chr: 11 Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Adult (90d-730d, breeding adult)
  brain, caudal vein plexus, corpus mamillare, cranial ganglion (all 33) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Mutagen Suppliers
fh309 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • fh310 Point Mutation ENU
    nlgn1_unrecovered Point Mutation ENU
    Targeting reagents: CRISPR1-nlgn1 (2), MO1-nlgn1 (1)
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nlgn1 HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process sprouting angiogenesis (more)
    Cellular Component excitatory synapse (more)
    Molecular Function neurexin family protein binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000460 (1)
  • InterPro:IPR002018 (1)
  • InterPro:IPR019819 (1)
  • InterPro:IPR029058 (1)
  • InterPro:IPR030022 (1)
  • PROSITE:PS00941 (1)
  • Pfam:PF00135 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nlgn1-001 (1) 2203
    nlgn1-002 (1) 153
    GENE PRODUCT DESCRIPTION
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM nlgn1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    nlgn1Contained in: [BAC] CH211-28A12 (1) (order this), CH211-119C22 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001142265 (1) 2544bp
    Genomic RefSeq:NW_001877143 (1) 458371bp Blast at MegaBLAST
    Polypeptide UniProtKB:D2X2F9 (1) 867aa
    Sequence Clusters UniGene:86013 (1)
    Sequence Information (all 21)
    OTHER nlgn1 GENE PAGES
  • Gene:100002610 (1)
  • VEGA:OTTDARG00000042143 (1)
  • Ensembl(GRCz10):ENSDARG00000077710 (1)
  • ORTHOLOGY for nlgn1 (Chr: 11)
    Species Symbol Chromosome Accession # Evidence
    Human NLGN1 3
  • Gene:22871
  • OMIM:600568
  • HGNC:14291
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (1)
    Mouse Nlgn1 3
  • MGI:2179435
  • Gene:192167
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (19)