Gene
nlgn1
- ID
- ZDB-GENE-090918-1
- Name
- neuroligin 1
- Symbol
- nlgn1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable neurexin family protein binding activity. Acts upstream of or within sprouting angiogenesis. Predicted to be located in membrane. Predicted to be active in postsynaptic specialization membrane. Is expressed in several structures, including brain; cardiovascular system; eye; gonad; and swim bladder. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human NLGN1 (neuroligin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Autism, susceptibility to, 20} | 618830 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Alpha/Beta hydrolase fold | Carboxylesterase, type B | Carboxylesterase type B, conserved site | Neuroligin | Neuroligin and Bile salt-activated lipase |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M6Z1K4
|
847 | |||||
|
UniProtKB:D2X2F9
|
867 | |||||
|
UniProtKB:A0A8M6Z363
|
827 | |||||
|
UniProtKB:B6EUL6
|
847 |
Interactions and Pathways
No data available
Plasmids
No data available