Gene
plekhg2
- ID
- ZDB-GENE-090819-1
- Name
- pleckstrin homology domain containing, family G (with RhoGef domain) member 2
- Symbol
- plekhg2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have guanyl-nucleotide exchange factor activity. Orthologous to human PLEKHG2 (pleckstrin homology and RhoGEF domain containing G2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Wei et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Leukodystrophy and acquired microcephaly with or without dystonia | 616763 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Dbl homology (DH) domain | Dbl homology (DH) domain superfamily | PH-like domain superfamily | PKHG1/2/3, pleckstrin homology (PH) domain | Pleckstrin homology domain |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PC17
|
2090 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
plekhg2-201
(1)
|
Ensembl | 7,811 nt | ||
| mRNA |
plekhg2-202
(1)
|
Ensembl | 6,979 nt |
Interactions and Pathways
No data available
Plasmids
No data available