Gene

kcnh5b

ID

ZDB-GENE-090319-1

Name

potassium voltage-gated channel, subfamily H (eag-related), member 5b

Symbol

kcnh5b Nomenclature History

Previous Names

si:ch211-251m13.1 (1)
zmp:0000000721 (1)

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to have voltage-gated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport and regulation of membrane potential. Predicted to localize to integral component of plasma membrane. Orthologous to human KCNH5 (potassium voltage-gated channel subfamily H member 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kcnh5b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Developmental and epileptic encephalopathy 112	620537

Associated With kcnh5b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000014	PAS domain
Domain	IPR000595	Cyclic nucleotide-binding domain
Domain	IPR000700	PAS-associated, C-terminal
Domain	IPR005821	Ion transport domain
Family	IPR003949	Potassium channel, voltage-dependent, EAG
Homologous_superfamily	IPR014710	RmlC-like jelly roll fold
Homologous_superfamily	IPR018490	Cyclic nucleotide-binding domain superfamily
Homologous_superfamily	IPR035965	PAS domain superfamily
Repeat	IPR001610	PAC motif

Domain Details Per Protein

Protein	Length	Cyclic nucleotide-binding domain	Cyclic nucleotide-binding domain superfamily	Ion transport domain	PAC motif	PAS-associated, C-terminal	PAS domain	PAS domain superfamily	Potassium channel, voltage-dependent, EAG	RmlC-like jelly roll fold
UniProtKB:A0A8M1RRD3 InterPro	1005

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	kcnh5b-201 (1) Ensembl	Ensembl	2,889 nt	Select Tool ZFIN BLAST
mRNA	kcnh5b-202 (1) Ensembl	Ensembl	2,025 nt	Select Tool
mRNA	kcnh5b-203 (1) Ensembl	Ensembl	2,934 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations