Gene
ndst3
- ID
- ZDB-GENE-090312-199
- Name
- N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
- Symbol
- ndst3 Nomenclature History
- Previous Names
-
- si:ch211-152j23.1
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable [heparan sulfate]-glucosamine N-sulfotransferase activity and deacetylase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Is expressed in central nervous system; dermis; fin; neural rod; and olfactory placode. Orthologous to human NDST3 (N-deacetylase and N-sulfotransferase 3) and NDST4 (N-deacetylase and N-sulfotransferase 4).
- Genome Resources
- Note
-
ndst3 is orthologous to NDST3 and NDST4. There appears to have been a tandem duplication after the divergence of ray-finned and lobe-finned fishes.
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Heparan sulfate sulfotransferase | Heparan sulphate-N-deacetylase | P-loop containing nucleoside triphosphate hydrolase | Sulfotransferase domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PIR7
|
579 | ||||
|
UniProtKB:A0A8M9Q484
|
874 | ||||
|
UniProtKB:E7F825
|
874 |
Interactions and Pathways
No data available
Plasmids
No data available