Gene
megf6a
- ID
- ZDB-GENE-090312-12
- Name
- multiple EGF-like-domains 6a
- Symbol
- megf6a Nomenclature History
- Previous Names
-
- si:dkey-25b23.2 (1)
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable calcium ion binding activity and scavenger receptor activity. Acts upstream of or within caudal fin morphogenesis and ossification involved in bone maturation. Is expressed in apical ectodermal ridge pectoral fin bud; head; notochord; and presumptive atrioventricular canal. Orthologous to human MEGF6 (multiple EGF like domains 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Teerlink et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR013032 | EGF-like, conserved site |
| Conserved_site | IPR018097 | EGF-like calcium-binding, conserved site |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001881 | EGF-like calcium-binding domain |
| Domain | IPR002049 | Laminin-type EGF domain |
| Domain | IPR011489 | EMI domain |
| Domain | IPR013111 | EGF-like domain, extracellular |
| Domain | IPR049883 | NOTCH1 EGF-like calcium-binding domain |
| Family | IPR052108 | Multiple EGF-like domains/Integrin beta-like |
| Homologous_superfamily | IPR009030 | Growth factor receptor cysteine-rich domain superfamily |
| PTM | IPR000152 | EGF-type aspartate/asparagine hydroxylation site |
Domain Details Per Protein
| Protein | Length | EGF-like calcium-binding, conserved site | EGF-like calcium-binding domain | EGF-like, conserved site | EGF-like domain | EGF-like domain, extracellular | EGF-type aspartate/asparagine hydroxylation site | EMI domain | Growth factor receptor cysteine-rich domain superfamily | Laminin-type EGF domain | Multiple EGF-like domains/Integrin beta-like | NOTCH1 EGF-like calcium-binding domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PWW0
|
1513 | |||||||||||
|
UniProtKB:A0A8M6Z4L7
|
1513 | |||||||||||
|
UniProtKB:A0A8M9Q7W7
|
1456 | |||||||||||
|
UniProtKB:A0A8M3AYG1
|
1456 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
megf6a-201
(1)
|
Ensembl | 4,272 nt | ||
| mRNA |
megf6a-202
(1)
|
Ensembl | 5,093 nt |
Interactions and Pathways
No data available
Plasmids
No data available