Gene

spock3

ID

ZDB-GENE-090311-24

Name

SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3

Symbol

spock3 Nomenclature History

Previous Names

im:7139568
si:dkey-285b22.1

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to have calcium ion binding activity; collagen binding activity; and extracellular matrix binding activity. Predicted to be involved in anatomical structure development. Predicted to localize to extracellular space. Is expressed in cardiovascular system; nervous system; and neural tube. Orthologous to human SPOCK3 (SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7139568 (12 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With spock3 Human Ortholog

No data available

Associated With spock3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR018247	EF-Hand 1, calcium-binding site
Domain	IPR000716	Thyroglobulin type-1
Domain	IPR002350	Kazal domain
Domain	IPR019577	SPARC/Testican, calcium-binding domain
Homologous_superfamily	IPR011992	EF-hand domain pair
Homologous_superfamily	IPR036058	Kazal domain superfamily
Homologous_superfamily	IPR036857	Thyroglobulin type-1 superfamily

Domain Details Per Protein

Protein	Length	EF-Hand 1, calcium-binding site	EF-hand domain pair	Kazal domain	Kazal domain superfamily	SPARC/Testican, calcium-binding domain	Thyroglobulin type-1	Thyroglobulin type-1 superfamily
UniProtKB:A0A0R4IMY5 InterPro	387
UniProtKB:F1RAX3 InterPro	384
UniProtKB:A0A8M6YZL5 InterPro	386
UniProtKB:A0A8M3BEW5 InterPro	389

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	spock3-201 (1) Ensembl	Ensembl	2,459 nt	Select Tool
mRNA	spock3-202 (1) Ensembl	Ensembl	1,039 nt	Select Tool
mRNA	spock3-203 (1) Ensembl	Ensembl	971 nt	Select Tool
mRNA	spock3-204 (1) Ensembl	Ensembl	1,322 nt	Select Tool
mRNA	spock3-205 (1) Ensembl	Ensembl	1,164 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations