Gene

dcaf6

ID

ZDB-GENE-090206-2

Name

ddb1 and cul4 associated factor 6

Symbol

dcaf6 Nomenclature History

Previous Names

iqwd1
si:rp71-20i5.1 (1)

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to enable transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to human DCAF6 (DDB1 and CUL4 associated factor 6).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dcaf6 Human Ortholog

No data available

Associated With dcaf6 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR045151	DDB1- and CUL4-associated factor 8-like
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat

Domain Details Per Protein

Protein	Length	DDB1- and CUL4-associated factor 8-like	WD40 repeat	WD40-repeat-containing domain superfamily	WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A0A8M2BFA9 InterPro	974
UniProtKB:B0QZE8 InterPro	907
UniProtKB:A0A8M2BFB1 InterPro	966
UniProtKB:A0A8M2BF97 InterPro	980
UniProtKB:A0A8M3AW71 InterPro	915
UniProtKB:A0A8M2BFX4 InterPro	988
UniProtKB:A0A8M2BFB4 InterPro	935