Gene
soat1
- ID
- ZDB-GENE-081105-177
- Name
- sterol O-acyltransferase 1
- Symbol
- soat1 Nomenclature History
- Previous Names
-
- si:dkey-21p1.4
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have cholesterol O-acyltransferase activity; cholesterol binding activity; and fatty-acyl-CoA binding activity. Predicted to be involved in cholesterol efflux; cholesterol esterification; and cholesterol metabolic process. Predicted to localize to endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in coronary artery disease and hepatocellular carcinoma. Is expressed in several structures, including eye; hatching gland; pericardial region; pleuroperitoneal region; and yolk syncytial layer. Orthologous to several human genes including SOAT1 (sterol O-acyltransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Chang et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Membrane bound O-acyl transferase, MBOAT | Sterol O-acyltransferase, ACAT/DAG/ARE types |
|---|---|---|---|
|
UniProtKB:B0UYE4
|
554 |
Interactions and Pathways
No data available
Plasmids
No data available