Gene
ranbp2
- ID
- ZDB-GENE-081104-93
- Name
- RAN binding protein 2
- Symbol
- ranbp2 Nomenclature History
- Previous Names
-
- nup358 (1)
- si:ch1073-55a19.2
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Enables SUMO ligase activity and molecular function activator activity. Acts upstream of or within cell projection assembly. Is active in annulate lamellae. Is expressed widely. Human ortholog(s) of this gene implicated in brain disease and inflammatory myofibroblastic tumor. Orthologous to several human genes including RANBP2 (RAN binding protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Magre et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Magre et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Encephalopathy, acute, infection-induced, 3, susceptibility to} | 608033 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020892 | Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site |
| Domain | IPR000156 | Ran binding domain |
| Domain | IPR001876 | Zinc finger, RanBP2-type |
| Domain | IPR002130 | Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain |
| Domain | IPR022011 | Nup358/RanBP2 E3 ligase domain |
| Family | IPR045255 | Ran binding protein RanBP1-like |
| Homologous_superfamily | IPR011990 | Tetratricopeptide-like helical domain superfamily |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR029000 | Cyclophilin-like domain superfamily |
| Homologous_superfamily | IPR036443 | Zinc finger, RanBP2-type superfamily |
| Repeat | IPR019734 | Tetratricopeptide repeat |
Domain Details Per Protein
| Protein | Length | Cyclophilin-like domain superfamily | Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site | Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain | Nup358/RanBP2 E3 ligase domain | PH-like domain superfamily | Ran binding domain | Ran binding protein RanBP1-like | Tetratricopeptide-like helical domain superfamily | Tetratricopeptide repeat | Zinc finger, RanBP2-type | Zinc finger, RanBP2-type superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9QJW3
|
2984 | |||||||||||
|
UniProtKB:A0A8M1RKE0
|
2958 | |||||||||||
|
UniProtKB:A0A8M9QFP1
|
2968 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ranbp2-201
(1)
|
Ensembl | 9,214 nt | ||
| mRNA |
ranbp2-202
(1)
|
Ensembl | 8,862 nt | ||
| mRNA |
ranbp2-203
(1)
|
Ensembl | 8,811 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-ranbp2 | polyclonal | Rabbit |
|
1 |
Plasmids
No data available