Gene
foxp3b
- ID
- ZDB-GENE-081104-332
- Name
- forkhead box P3b
- Symbol
- foxp3b Nomenclature History
- Previous Names
-
- si:dkey-16n15.5 (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in head kidney. Human ortholog(s) of this gene implicated in immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome; pulmonary tuberculosis; and type 1 diabetes mellitus. Orthologous to human FOXP3 (forkhead box P3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Immunodysregulation, polyendocrinopathy, and enteropathy, X-linked | 304790 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR030456 | Fork head domain conserved site 2 |
Domain | IPR001766 | Fork head domain |
Domain | IPR032354 | FOXP, coiled-coil domain |
Domain | IPR047413 | Forkhead box protein P3, forkhead domain |
Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Domain Details Per Protein
Protein | Length | Forkhead box protein P3, forkhead domain | Fork head domain | Fork head domain conserved site 2 | FOXP, coiled-coil domain | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
---|---|---|---|---|---|---|---|
UniProtKB:A0A8M9PRD6
|
237 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
foxp3b-201
(1)
|
Ensembl | 2051 nt | |
mRNA |
foxp3b-202
(1)
|
Havana | 1131 nt | |
mRNA |
foxp3b-203
(1)
|
Ensembl | 2139 nt |
Interactions and Pathways
No data available
Plasmids
No data available