Gene

agtpbp1

ID

ZDB-GENE-081104-267

Name

ATP/GTP binding carboxypeptidase 1

Symbol

agtpbp1 Nomenclature History

Previous Names

CCP1 (1)
si:ch73-236b16.2

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to have metallocarboxypeptidase activity and tubulin binding activity. Involved in T cell differentiation in thymus and chordate embryonic development. Predicted to localize to cytosol; mitochondrion; and nucleus. Is expressed in Kupffer's vesicle; blastomere; nervous system; pronephric duct; and somite. Orthologous to human AGTPBP1 (ATP/GTP binding protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 6 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With agtpbp1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neurodegeneration, childhood-onset, with cerebellar atrophy	618276

Associated With agtpbp1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000834	Peptidase M14, carboxypeptidase A
Domain	IPR033852	Cytosolic aminopeptidase 1/4
Domain	IPR040626	Cytosolic carboxypeptidase, N-terminal
Family	IPR050821	Cytosolic carboxypeptidase
Homologous_superfamily	IPR011989	Armadillo-like helical
Homologous_superfamily	IPR016024	Armadillo-type fold

Domain Details Per Protein

Protein	Length	Armadillo-like helical	Armadillo-type fold	Cytosolic aminopeptidase 1/4	Cytosolic carboxypeptidase	Cytosolic carboxypeptidase, N-terminal	Peptidase M14, carboxypeptidase A
UniProtKB:Q4U2V3 InterPro	1153
UniProtKB:A0A0R4IG37 InterPro	1153

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	agtpbp1-201 (1) Ensembl	Ensembl	3,675 nt	Select Tool ZFIN BLAST
mRNA	agtpbp1-202 (1) Ensembl	Ensembl	2,294 nt	Select Tool
mRNA	cu694202.1-201 (1) Ensembl	Ensembl	122 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations