Gene

si:ch73-173h19.3

ID

ZDB-GENE-081104-245

Name

si:ch73-173h19.3

Symbol

si:ch73-173h19.3 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Predicted to enable calcium ion binding activity and epidermal growth factor receptor activity. Predicted to act upstream of or within epidermal growth factor receptor signaling pathway. Predicted to be located in collagen-containing extracellular matrix. Human ortholog(s) of this gene implicated in Doyne honeycomb retinal dystrophy. Orthologous to human EFEMP1 (EGF containing fibulin extracellular matrix protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With si:ch73-173h19.3 Human Ortholog

No data available

Associated With si:ch73-173h19.3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018097	EGF-like calcium-binding, conserved site
Domain	IPR000742	EGF-like domain
Domain	IPR001881	EGF-like calcium-binding domain
Domain	IPR026823	Complement Clr-like EGF domain
Domain	IPR049883	NOTCH1 EGF-like calcium-binding domain
Family	IPR050751	Extracellular matrix structural protein
Homologous_superfamily	IPR009030	Growth factor receptor cysteine-rich domain superfamily
PTM	IPR000152	EGF-type aspartate/asparagine hydroxylation site