Gene
ep400
- ID
- ZDB-GENE-081104-186
- Name
- E1A binding protein p400
- Symbol
- ep400 Nomenclature History
- Previous Names
-
- si:ch211-227i14.2
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable chromatin binding activity. Predicted to be involved in DNA repair. Predicted to be located in nucleoplasm. Predicted to be part of NuA4 histone acetyltransferase complex and Swr1 complex. Orthologous to several human genes including EP400 (E1A binding protein p400).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa1673 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa5775 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa21364 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa21365 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa27259 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa38707 | Allele with one point mutation | Unknown | Splice Site | ENU |
1 - 6 of 6
Show
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| MO1-ep400 | N/A | Huang et al., 2013 |
| MO2-ep400 | N/A | Huang et al., 2013 |
1 - 2 of 2
Show
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | E1A-binding protein p400, N-terminal | Helicase, C-terminal domain-like | Helicase/SANT-associated domain | Helicase superfamily 1/2, ATP-binding domain | P-loop containing nucleoside triphosphate hydrolase | SANT/Myb domain | SNF2-like, N-terminal domain superfamily | SNF2, N-terminal | SNF2/RAD5-like, C-terminal helicase domain |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3BC09 | InterPro | 3108 | |||||||||
| UniProtKB:A0A8M3B277 | InterPro | 3091 | |||||||||
| UniProtKB:A0A8M3BC14 | InterPro | 3105 | |||||||||
| UniProtKB:A0A8M3AVF6 | InterPro | 3069 | |||||||||
| UniProtKB:A0A8M3B551 | InterPro | 3098 |
1 - 5 of 19 Show all
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-227I14 | ZFIN Curated Data | |
| Contained in | Fosmid | CH1073-151C15 | ZFIN Curated Data |
1 - 2 of 2
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_068223188 (1) | 11005 nt | ||
| Genomic | GenBank:AL929056 (1) | 157468 nt | ||
| Polypeptide | UniProtKB:A0AB32TZR9 (1) | 3163 aa |
- Trivellin, G., Tirosh, A., Hernández-Ramírez, L.C., Gupta, T., Tsai-Morris, C.H., Faucz, F.R., Burgess, H.A., Feldman, B., Stratakis, C.A. (2020) The X-linked acrogigantism-associated gene gpr101 is a regulator of early embryonic development and growth in zebrafish. Molecular and Cellular Endocrinology. 520:111091
- Huang, H.T., Kathrein, K.L., Barton, A., Gitlin, Z., Huang, Y.H., Ward, T.P., Hofmann, O., Dibiase, A., Song, A., Tyekucheva, S., Hide, W., Zhou, Y., and Zon, L.I. (2013) A network of epigenetic regulators guides developmental haematopoiesis in vivo. Nature cell biology. 15(12):1516-1525
1 - 2 of 2
Show