Gene
mapta
- ID
- ZDB-GENE-081027-1
- Name
- microtubule-associated protein tau a
- Symbol
- mapta Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have microtubule binding activity. Predicted to localize to cytoplasm and microtubule. Human ortholog(s) of this gene implicated in dementia (multiple); neurodegenerative disease (multiple); progressive supranuclear palsy; and temporal lobe epilepsy. Is expressed in central nervous system; chordo neural hinge; hypochord; and retinal ganglion cell. Orthologous to human MAPT (microtubule associated protein tau).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| frontotemporal dementia | Alliance | Frontotemporal dementia 1, with or without parkinsonism | 600274 |
| late onset Parkinson's disease | Alliance | {Parkinson disease, susceptibility to} | 168600 |
| Pick's disease | Alliance | Pick disease | 172700 |
| progressive supranuclear palsy | Alliance | Supranuclear palsy, progressive | 601104 |
| Supranuclear palsy, progressive atypical | 260540 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
Interactions and Pathways
No data available
Plasmids
No data available