Gene
srms
- ID
- ZDB-GENE-081022-95
- Name
- src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
- Symbol
- srms Nomenclature History
- Previous Names
-
- zgc:194282
- zgc:194283
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Predicted to be involved in several processes, including cell migration; peptidyl-tyrosine autophosphorylation; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to localize to extrinsic component of cytoplasmic side of plasma membrane. Orthologous to human SRMS (src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Active_site | IPR008266 | Tyrosine-protein kinase, active site |
Binding_site | IPR017441 | Protein kinase, ATP binding site |
Domain | IPR000719 | Protein kinase domain |
Domain | IPR000980 | SH2 domain |
Domain | IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain |
Domain | IPR001452 | SH3 domain |
Domain | IPR020635 | Tyrosine-protein kinase, catalytic domain |
Family | IPR050198 | Non-receptor tyrosine kinases involved in cell signaling |
Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
Homologous_superfamily | IPR036860 | SH2 domain superfamily |
Domain Details Per Protein
Protein | Length | Non-receptor tyrosine kinases involved in cell signaling | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine-threonine/tyrosine-protein kinase, catalytic domain | SH2 domain | SH2 domain superfamily | SH3 domain | SH3-like domain superfamily | Tyrosine-protein kinase, active site | Tyrosine-protein kinase, catalytic domain |
---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:X1WHM4
|
492 |
Interactions and Pathways
No data available
Plasmids
No data available