Gene
uroc1
- ID
- ZDB-GENE-081022-148
- Name
- urocanate hydratase 1
- Symbol
- uroc1 Nomenclature History
- Previous Names
-
- zgc:194768
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable urocanate hydratase activity. Predicted to be involved in histidine catabolic process. Predicted to act upstream of or within histidine metabolic process. Human ortholog(s) of this gene implicated in urocanase deficiency. Orthologous to human UROC1 (urocanate hydratase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| urocanase deficiency | Alliance | ?Urocanase deficiency | 276880 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR023636 | Urocanase conserved site |
| Domain | IPR035085 | Urocanase, Rossmann-like domain |
| Domain | IPR035400 | Urocanase, N-terminal domain |
| Domain | IPR035401 | Urocanase, C-terminal domain |
| Homologous_superfamily | IPR036190 | Urocanase superfamily |
| Homologous_superfamily | IPR038364 | Urocanase, central domain superfamily |
Domain Details Per Protein
| Protein | Length | Urocanase, central domain superfamily | Urocanase conserved site | Urocanase, C-terminal domain | Urocanase, N-terminal domain | Urocanase, Rossmann-like domain | Urocanase superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:B3DJ54
|
675 |
Interactions and Pathways
No data available
Plasmids
No data available