Gene
prdm16
- ID
- ZDB-GENE-080613-2
- Name
- PR domain containing 16
- Symbol
- prdm16 Nomenclature History
- Previous Names
-
- fc09g08
- si:ch211-263k4.2
- wu:fc09g08 (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have metal ion binding activity and nucleic acid binding activity. Involved in several processes, including cardiac muscle cell proliferation; embryonic cranial skeleton morphogenesis; and hematopoietic stem cell differentiation. Is expressed in several structures, including hindbrain neural rod; nervous system; pectoral fin bud; pronephric duct; and stomodeum. Orthologous to human PRDM16 (PR/SET domain 16).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| dilated cardiomyopathy 1LL | Alliance | Cardiomyopathy, dilated, 1LL | 615373 |
| dilated cardiomyopathy 1LL | Alliance | Left ventricular noncompaction 8 | 615373 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | PRDM16, PR/SET domain | SET domain | SET domain superfamily | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2BEM7
|
1302 | |||||
|
UniProtKB:A0A8M9QJ45
|
1180 | |||||
|
UniProtKB:A0A8M3BC36
|
1297 | |||||
|
UniProtKB:A0A8M9Q420
|
1332 | |||||
|
UniProtKB:A0A8M9PRJ8
|
1335 | |||||
|
UniProtKB:A0A8M1QVB6
|
1298 | |||||
|
UniProtKB:A0A8M9QEA0
|
1336 | |||||
|
UniProtKB:A0A8M9QA80
|
1238 | |||||
|
UniProtKB:A0A8M2BES0
|
1308 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
si:ch211-263k4.2-202
(1)
|
Havana | 2783 nt |
Interactions and Pathways
No data available
Plasmids
No data available