Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-080519-3
Gene Name: nuclear receptor binding SET domain protein 1a
Gene Symbol: nsd1a
Location: Chr: 14   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. S6 from Sun et al., 2008
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la019080Tg, la027572Tg, sa13619
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Beckwith-Wiedemann syndrome 130650
Leukemia, acute myeloid 601626
Sotos syndrome 1 117550
GENE ONTOLOGY
Ontology GO Term
Biological Process methylation (more)
Cellular Component nucleus (more)
Molecular Function histone-lysine N-methyltransferase activity (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000313 (1)
  • InterPro:IPR001214 (1)
  • InterPro:IPR001841 (1)
  • InterPro:IPR001965 (1)
  • InterPro:IPR003616 (1)
  • InterPro:IPR006560 (1)
  • InterPro:IPR011011 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR019786 (1)
  • InterPro:IPR019787 (1)
  • PROSITE:PS01359 (1)
  • PROSITE:PS50016 (1)
  • PROSITE:PS50280 (1)
  • PROSITE:PS50812 (1)
  • PROSITE:PS50868 (1)
  • PROSITE:PS51215 (1)
  • Pfam:PF00628 (1)
  • Pfam:PF00855 (1)
  • Pfam:PF00856 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nsd1a-001 (1) 6701
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM nsd1a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    nsd1a Contained in: [Fosmid] CH1073-100E22 (1) (order this), CH1073-452F17 (1) (order this), CH1073-527A6 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_678798 (1) 7733 bp
    Genomic GenBank:CU659412 (1) 36841 bp
    Select Tool
    Polypeptide UniProtKB:F1QA79 (1) 2055 aa
    Sequence Clusters UniGene:83733 (1)
    Sequence Information (all 14)
    OTHER nsd1a GENE PAGES
  • Gene:556086 (1)
  • VEGA:OTTDARG00000034925 (1)
  • Ensembl(Zv9):ENSDARG00000060016 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish nsd1a 14  
    Human NSD1 5 (5q35)
  • OMIM:606681
  • Gene:64324
  • Mouse Nsd1 13 ( 29.80 cM)
  • MGI:1276545
  • Gene:18193
  • Orthology Details
    CITATIONS (19)