Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-080519-2
Gene Name: nuclear receptor binding SET domain protein 1b
Gene Symbol: nsd1b
Location: Chr: 21   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. S6 from Sun et al., 2008
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Blastula:Sphere (4.0h-4.33h)
  whole organism
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa24006
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Beckwith-Wiedemann syndrome 130650
Leukemia, acute myeloid 601626
Sotos syndrome 1 117550
GENE ONTOLOGY
Ontology GO Term
Biological Process methylation (more)
Cellular Component nucleus (more)
Molecular Function histone-lysine N-methyltransferase activity (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000313 (1)
  • InterPro:IPR001214 (1)
  • InterPro:IPR001965 (1)
  • InterPro:IPR003616 (1)
  • InterPro:IPR006560 (1)
  • InterPro:IPR011011 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR019786 (1)
  • InterPro:IPR019787 (1)
  • PROSITE:PS01359 (1)
  • PROSITE:PS50016 (1)
  • PROSITE:PS50280 (1)
  • PROSITE:PS50812 (1)
  • PROSITE:PS50868 (1)
  • PROSITE:PS51215 (1)
  • Pfam:PF00628 (1)
  • Pfam:PF00855 (1)
  • Pfam:PF00856 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nsd1b-001 (1) 5720
    ncRNA nsd1b-002 (1) 464
    mRNA nsd1b-003 (1) 906
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM nsd1b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    nsd1b Contained in: [BAC] DKEY-13F9 (1), DKEY-106J22
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005173883 (1) 6859 bp
    Genomic GenBank:BX842703 (1) 208780 bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1Q9U9 (1) 1873 aa
    Sequence Clusters UniGene:119918 (1)
    Sequence Information (all 24)
    OTHER nsd1b GENE PAGES
  • Gene:564592 (1)
  • VEGA:OTTDARG00000031645 (1)
  • Ensembl(Zv9):ENSDARG00000060705 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish nsd1b 21  
    Human NSD1 5 (5q35)
  • OMIM:606681
  • Gene:64324
  • Mouse Nsd1 13 ( 29.80 cM)
  • MGI:1276545
  • Gene:18193
  • Orthology Details
    CITATIONS (13)