Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-080515-3
Gene Name: euchromatic histone-lysine N-methyltransferase 1b
Gene Symbol: ehmt1b
Location: Chr: 21   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. S6 from Sun et al., 2008
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Blastula:Sphere (4.0h-4.33h)
  whole organism
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la021819Tg, sa13273, sa17604
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Kleefstra syndrome 610253
GENE ONTOLOGY
Ontology GO Term
Biological Process histone lysine methylation (more)
Cellular Component chromosome (more)
Molecular Function histone-lysine N-methyltransferase activity (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001214 (1)
  • InterPro:IPR002110 (1)
  • InterPro:IPR003606 (1)
  • InterPro:IPR007728 (1)
  • InterPro:IPR020683 (1)
  • PROSITE:PS50088 (1)
  • PROSITE:PS50280 (1)
  • PROSITE:PS50297 (1)
  • PROSITE:PS50867 (1)
  • Pfam:PF00856 (1)
  • Pfam:PF05033 (1)
  • Pfam:PF12796 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ehmt1b-001 (1) 4502
    ncRNA ehmt1b-002 (1) 918
    ehmt1b-003 (1) 862
    ehmt1b-004 (1) 625
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM ehmt1b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    ehmt1b Contained in: [BAC] CH73-38J13 (1) (order this), DKEY-16H22
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001172564 (1) 5362 bp
    Genomic GenBank:CR936260 212463 bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1QJX1 (1) 1286 aa
    Sequence Clusters UniGene:132728 (1)
    Sequence Information (all 24)
    OTHER ehmt1b GENE PAGES
  • Gene:402830 (1)
  • VEGA:OTTDARG00000032105 (1)
  • Ensembl(Zv9):ENSDARG00000026634 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish ehmt1b 21  
    Human EHMT1 9 (9q34.3)
  • OMIM:607001
  • Gene:79813
  • Mouse Ehmt1 2 ( 16.73 cM)
  • MGI:1924933
  • Gene:77683
  • Orthology Details
    CITATIONS (16)