ZFIN ID: ZDB-GENE-080515-3
Gene Name: euchromatic histone-lysine N-methyltransferase 1b
Gene Symbol: ehmt1b
Location: Chr: 21   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. S6 from Sun et al., 2008
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Blastula:Sphere (4.0h-4.33h)
  whole organism
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la021819Tg, sa13273, sa17604
Knockdown reagents: MO1-ehmt1b (1)
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Kleefstra syndrome 610253
GENE ONTOLOGY
Ontology GO Term
Biological Process histone lysine methylation (more)
Cellular Component chromosome (more)
Molecular Function histone-lysine N-methyltransferase activity (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001214 (1)
  • InterPro:IPR002110 (1)
  • InterPro:IPR003606 (1)
  • InterPro:IPR007728 (1)
  • InterPro:IPR020683 (1)
  • PROSITE:PS50088 (1)
  • PROSITE:PS50280 (1)
  • PROSITE:PS50297 (1)
  • PROSITE:PS50867 (1)
  • Pfam:PF00856 (1)
  • Pfam:PF05033 (1)
  • Pfam:PF12796 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ehmt1b-001 (1) 4502
    ncRNA ehmt1b-002 (1) 918
    ehmt1b-003 (1) 862
    ehmt1b-004 (1) 625
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ehmt1b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    ehmt1b Contained in: [BAC] CH73-38J13 (1) (order this), DKEY-16H22
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001172564 (1) 5362 bp
    Genomic GenBank:CR936260 212463 bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1QJX1 (1) 1286 aa
    Sequence Clusters UniGene:132728 (1)
    Sequence Information (all 30)
    OTHER ehmt1b GENE PAGES
  • Gene:402830 (1)
  • VEGA:OTTDARG00000032105 (1)
  • Ensembl(Zv9):ENSDARG00000026634 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish ehmt1b 21  
    Human EHMT1 9 (9q34.3)
  • OMIM:607001
  • Gene:79813
  • Mouse Ehmt1 2 ( 16.73 cM)
  • MGI:1924933
  • Gene:77683
  • Orthology Details
    CITATIONS (17)