Gene
eif2ak2
- ID
- ZDB-GENE-080422-1
- Name
- eukaryotic translation initiation factor 2-alpha kinase 2
- Symbol
- eif2ak2 Nomenclature History
- Previous Names
-
- PKR (1)
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Exhibits protein kinase activity. Predicted to be involved in methylation and protein phosphorylation. Is expressed in several structures, including eye; heart; integument; liver; and pleuroperitoneal region.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Rothenburg et al., 2008
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR014720 | Double-stranded RNA-binding domain |
| Domain | IPR044452 | EIF2AK2, first double-stranded RNA binding domain |
| Family | IPR050339 | Cell Cycle and Stress Response Kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Cell Cycle and Stress Response Kinase | Double-stranded RNA-binding domain | EIF2AK2, first double-stranded RNA binding domain | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A9YT50
|
682 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available