Gene
nr1h5
- ID
- ZDB-GENE-080403-3
- Name
- nuclear receptor subfamily 1, group H, member 5
- Symbol
- nr1h5 Nomenclature History
- Previous Names
-
- FXRbeta (1)
- gb:dq017614
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have several functions, including DNA-binding transcription factor activity; RNA polymerase II regulatory region sequence-specific DNA binding activity; and nuclear receptor transcription coactivator activity. Predicted to be involved in several processes, including cellular response to lipopolysaccharide; cholesterol homeostasis; and regulation of transcription by RNA polymerase II. Predicted to localize to RNA polymerase II transcription factor complex. Is expressed in liver and yolk syncytial layer.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2008
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- dq017614 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000536 | Nuclear hormone receptor, ligand-binding domain |
| Domain | IPR001628 | Zinc finger, nuclear hormone receptor-type |
| Family | IPR001723 | Nuclear hormone receptor |
| Family | IPR050234 | Nuclear hormone receptor family NR1 subfamily |
| Homologous_superfamily | IPR013088 | Zinc finger, NHR/GATA-type |
| Homologous_superfamily | IPR035500 | Nuclear hormone receptor-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Nuclear hormone receptor | Nuclear hormone receptor family NR1 subfamily | Nuclear hormone receptor, ligand-binding domain | Nuclear hormone receptor-like domain superfamily | Zinc finger, NHR/GATA-type | Zinc finger, nuclear hormone receptor-type |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2BEQ0
|
487 | ||||||
|
UniProtKB:B0S5T9
|
486 |
Interactions and Pathways
No data available
Plasmids
No data available