Gene
gbgt1l5
- ID
- ZDB-GENE-080402-11
- Name
- globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 5
- Symbol
- gbgt1l5 Nomenclature History
- Previous Names
-
- FS-L5 (1)
- abo
- si:dkey-16g11.2
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable glycosyltransferase activity. Predicted to be involved in lipid glycosylation. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be located in membrane. Predicted to be active in Golgi apparatus and vesicle. Human ortholog(s) of this gene implicated in several diseases, including Plasmodium falciparum malaria; graft-versus-host disease; leukemia (multiple); lung disease (multiple); and severe acute respiratory syndrome. Orthologous to several human genes including GBGT1 (globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group)).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| la015615Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| sa17087 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Glycosyl transferase, family 6 | Nucleotide-diphospho-sugar transferases |
|---|---|---|---|
|
UniProtKB:B0S7I1
|
304 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-16G11 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001123269 (1) | |||
| Genomic | GenBank:BX842571 (1) | 145925 nt | ||
| Polypeptide | UniProtKB:B0S7I1 (1) | 304 aa |
No data available
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
- Turcot-Dubois, A.L., Le Moullac-Vaidye, B., Despiau, S., Roubinet, F., Bovin, N., Le Pendu, J., and Blancher, A. (2007) Long Term Evolution of the Cazy Glycosyltransferase 6 (ABO) Gene Family from Fishes to Mammals: A Birth-and-Death Evolution Model. Glycobiology. 17(5):516-528
- Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
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