Gene
rnf139
- ID
- ZDB-GENE-080401-4
- Name
- ring finger protein 139
- Symbol
- rnf139 Nomenclature History
- Previous Names
-
- zgc:175173
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ERAD pathway and proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in membrane. Predicted to be part of Derlin-1 retrotranslocation complex. Predicted to be active in endomembrane system. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human RNF139 (ring finger protein 139).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| nonpapillary renal cell carcinoma | Alliance | Renal cell carcinoma | 144700 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | HRD1 family E3 ubiquitin-protein ligases | TRC8-like, N-terminal domain | Zinc finger, RING-CH-type | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type |
|---|---|---|---|---|---|---|---|
| UniProtKB:B1H1M0 | InterPro | 664 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rnf139-201
(1)
|
Ensembl | 2,861 nt |
Interactions and Pathways
No data available
Plasmids
No data available