Gene

lrrc4cb

ID

ZDB-GENE-080327-5

Name

leucine rich repeat containing 4C, genome duplicate b

Symbol

lrrc4cb Nomenclature History

Previous Names

sc:d0316 (1)
si:dkey-6l15.1

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to enable cell-cell adhesion mediator activity. Predicted to be involved in modulation of chemical synaptic transmission; regulation of axonogenesis; and synaptic membrane adhesion. Predicted to be located in membrane. Predicted to be active in glutamatergic synapse and postsynaptic density membrane. Is expressed in basal plate midbrain region and central nervous system. Orthologous to human LRRC4C (leucine rich repeat containing 4C).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cssl:d0316 (11 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With lrrc4cb Human Ortholog

No data available

Associated With lrrc4cb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000372	Leucine-rich repeat N-terminal domain
Domain	IPR000483	Cysteine-rich flanking region, C-terminal
Domain	IPR003598	Immunoglobulin subtype 2
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013098	Immunoglobulin I-set
Family	IPR050541	Leucine-rich repeat and transmembrane domain-containing protein
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR032675	Leucine-rich repeat domain superfamily
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily
Repeat	IPR001611	Leucine-rich repeat
Repeat	IPR003591	Leucine-rich repeat, typical subtype

Domain Details Per Protein

Protein	Length	Cysteine-rich flanking region, C-terminal	Immunoglobulin domain subtype	Immunoglobulin I-set	Immunoglobulin-like domain	Immunoglobulin-like domain superfamily	Immunoglobulin-like fold	Immunoglobulin subtype 2	Leucine-rich repeat	Leucine-rich repeat and transmembrane domain-containing protein	Leucine-rich repeat domain superfamily	Leucine-rich repeat N-terminal domain	Leucine-rich repeat, typical subtype
UniProtKB:F1QCU7 InterPro	631

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	lrrc4c (1 of many)-202 (1) Ensembl	Ensembl		4,447 nt	Select Tool ZFIN BLAST
mRNA	lrrc4cb-201 (1) Ensembl	Ensembl		1,896 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations