Gene
nfasca
- ID
- ZDB-GENE-080229-6
- Name
- neurofascin homolog (chicken) a
- Symbol
- nfasca Nomenclature History
- Previous Names
-
- sc:d0205
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to be involved in nervous system development; synapse organization; and transmission of nerve impulse. Predicted to localize to integral component of membrane. Is expressed in nervous system; pancreatic system; and trigeminal placode. Orthologous to human NFASC (neurofascin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cssl:d205 (25 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Vagionitis et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental disorder with central and peripheral motor dysfunction | 618356 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003006 | Immunoglobulin/major histocompatibility complex, conserved site |
| Domain | IPR003598 | Immunoglobulin subtype 2 |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR003961 | Fibronectin type III |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013098 | Immunoglobulin I-set |
| Domain | IPR026965 | Neurofascin, immunoglobulin-like domain |
| Domain | IPR026966 | Neurofascin/L1/NrCAM, C-terminal domain |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin domain subtype | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin/major histocompatibility complex, conserved site | Immunoglobulin subtype 2 | Neurofascin, immunoglobulin-like domain | Neurofascin/L1/NrCAM, C-terminal domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PUN4
|
1168 | |||||||||||
|
UniProtKB:A0A8M9QHH2
|
1379 | |||||||||||
|
UniProtKB:C0L978
|
1369 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nfasca-201
(1)
|
Ensembl | 6,288 nt | ||
| mRNA |
nfasca-202
(1)
|
Ensembl | 9,923 nt | ||
| mRNA |
nfasca-203
(1)
|
Ensembl | 4,007 nt | ||
| mRNA |
nfasca-204
(1)
|
Ensembl | 4,110 nt | ||
| mRNA |
nfasca-205
(1)
|
Ensembl | 4,066 nt |
Interactions and Pathways
No data available
Plasmids
No data available