Gene
fmn2b
- ID
- ZDB-GENE-080225-35
- Name
- formin 2b
- Symbol
- fmn2b Nomenclature History
- Previous Names
-
- im:7158925
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable microtubule binding activity. Predicted to be involved in intracellular transport. Predicted to act upstream of or within actin nucleation. Predicted to be located in actin filament. Predicted to be active in endoplasmic reticulum membrane and nucleus. Is expressed in central nervous system and retinal ganglion cell layer. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 47. Orthologous to human FMN2 (formin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7158925 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Nagar et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive intellectual developmental disorder 47 | Alliance | Intellectual developmental disorder, autosomal recessive 47 | 616193 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Formin, FH2 domain | Formin, FH2 domain superfamily | Formin homology family, Cappuccino subfamily |
|---|---|---|---|---|
|
UniProtKB:A0A2R8QAK8
|
1479 | |||
|
UniProtKB:A0A8M3B7Q6
|
1473 | |||
|
UniProtKB:A0A8M3AYR9
|
869 | |||
|
UniProtKB:A0A8M3B4X8
|
1460 |
Interactions and Pathways
No data available
Plasmids
No data available