Gene
pigw
- ID
- ZDB-GENE-080204-94
- Name
- phosphatidylinositol glycan anchor biosynthesis, class W
- Symbol
- pigw Nomenclature History
- Previous Names
-
- zgc:175274
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable glucosaminyl-phosphatidylinositol O-acyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in hyperphosphatasia with impaired intellectual development syndrome 5. Orthologous to human PIGW (phosphatidylinositol glycan anchor biosynthesis class W).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hyperphosphatasia with impaired intellectual development syndrome 5 | Alliance | Glycosylphosphatidylinositol biosynthesis defect 11 | 616025 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR009447 | Phosphatidylinositol anchor biosynthesis protein PIGW/GWT1 |
Domain Details Per Protein
| Protein | Additional Resources | Length | Phosphatidylinositol anchor biosynthesis protein PIGW/GWT1 |
|---|---|---|---|
| UniProtKB:F1QAR3 | InterPro | 490 |
Interactions and Pathways
No data available
Plasmids
No data available