Gene

hmx1

ID
ZDB-GENE-080204-54
Name
H6 family homeobox 1
Symbol
hmx1 Nomenclature History
Previous Names
  • im:7155045
  • nkx5-3 (1)
  • nkx5.3 (1)
  • zgc:172164
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have sequence-specific DNA binding activity. Involved in retinal cone cell development. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in oculoauricular syndrome. Is expressed in immature eye; neural plate; otic vesicle; pharyngeal arch; and sensory system. Orthologous to human HMX1 (H6 family homeobox 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 9 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
11 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hmx1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
oculoauricular syndrome Alliance Oculoauricular syndrome 612109
Associated With hmx1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR020479 Homeobox domain, metazoa
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox domain, metazoa Homeobox-like domain superfamily
UniProtKB:A9Y2A9 282
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations